Significant Inhibition of Tumor Growth following Single Dose Nanoparticle-Enhanced Photodynamic Therapy
Figure 6
(a) Histological staining of the excised tumor sections on treatment day 1 of (i) saline with no photoirradiation (control), (ii) MSN-PdTPP with photoirradiation at 0 h after injection, (iii) MSN-PdTPP with photoirradiation at 1 h after injection, and on treatment day 28 of (iv) MSN-PdTPP with photoirradiation at 1 h after injection. H&E staining; scale bars: 200 μm. (b) TUNEL staining of consecutive sections for each group at 200x magnification (upper, scale bars: 200 μm) and 1000x magnification (upper, scale bars: 50 μm). (c) Caspase-3 staining of consecutive sections for each group at 200x magnification (upper, scale bars: 200 μm) and 1000x magnification (upper, scale bars: 50 μm).
