Influence of Zinc Supplementation in Acute Diarrhea Differs by the Isolated Organism

Figure 2

Statistical evaluation of the bivariate interactions between zinc supplementation and each of the four major isolates for two diarrhea-related outcomes—risk of continued diarrhea for 3 or more days (left column) and high stool volume (right column). The interaction was quantified using the interaction contrast statistic [14], the significance was tested using the Breslow-Day (B-D P) test for heterogeneity, and statistical power of interpretation in the present study was determined using the 𝜃 statistic described by Gönen [14]. Interaction contrast exceeding or below zero indicates a detrimental or protective interaction, respectively.