Clinical Study
An Evaluation of Initial Vancomycin Dosing in Infants, Children, and Adolescents
| | Parameters | Infant
| Child | Adolescent |
| | Room, No. (%) | | | | | General Pediatric | 6 (66.7) | 12 (100) | 4 (100) | | PICU | 3 (33.3) | — | — | | Gender, No. (%) | | | | | Male | 4 (44.4) | 5 (41.7) | 4 (100) | | Race, No. (%) | | | | | Caucasian | 4 (44.4) | 7 (58.3) | 2 (50) | | African American | 3 (33.3) | 4 (33.3) | 2 (50) | | Hispanic | 2 (22.2) | — | — | | Asian | — | 1 (8.3) | — | | Mean age, yrs (range) | 0.78
(1–23 months) | 5.3
(2–12) | 14.8
(13–17) | | Mean initial creatinine level, mg/dL (range) | 0.4
(0.3–0.5) | 0. 4
(0.3–0.7) | 0.6
(0.3–0.8) | | Timing of level, No. (%) | | | | | Before 3rd dose | 4 (44.4) | 6 (50) | 3 (75) | | Before 4th dose | 3 (33.3) | 5 (41.7) | — | | Before >4th dose | 2 (22.2) | 1 (8.3) | 1 (25) | | Mean duration of therapy, days (range) | 4.9 (1–21) | 3.8 (1–16) | 2.5 (1–4) |
|
|
