Outcomes of Neonatal Candidiasis: The Impact of Delayed Initiation of Antifungal Therapy

Table 1

Mortality risk factors: comparison between nonsurvivor and survivor groups.

	Nonsurvivors; 𝑛=22	Survivors; 𝑛=41	𝑃 value
Number of positive fungal cultures, mean	5.0	2.6	0.001
Platelet count nadir during IFI: 1000 cells/mm^3, mean	38	73	0.01
NICU stay at time of first positive fungal culture (mean, days)	69.5	32.8	0.004
Postconceptional age at time of positive culture (mean, weeks)	35.1	40.5	0.03
Gestational Age
≤26	10	19
27–32	1	6
33–37	6	5
Term	5	11
Gender
Male	13	17
Female	9	24
Congenital heart disease
Yes	5	10
No	17	31
Age (days) at time of first positive fungal culture
≤14	4	14
15–28	4	10
29–60	4	12
61–120	6	4
>120	4	1
Time on mechanical ventilation before first positive fungal culture (mean, days)	46.0	21.6	0.002
Time with CVC before first positive fungal culture (mean, days)	60.1	31.1	0.001
Time with urinary catheter before first positive fungal culture (mean, days)	7.5	14.4	0.06
Time between first positive culture and initiation of therapy (median, days)	4	2	0.001