Clinical Study

Maternal BMI, IGF-I Levels, and Birth Weight in African American and White Infants

Table 3

1Adjusted regression coefficients and standard errors (SE) for the associations between newborn IGF-I and Birth Weight in African American and White infants.

Birth weight
All
( )
African American
( )
Whites
( )
Maternal BMI < 30
( )
Maternal BMI ≥ 30
( )
-coefficient, SE,
value
-coefficient, SE,
value
-coefficient, SE,
value
-coefficient, SE,
value
-coefficient, SE,
value

High IGF-I**230.46, 58.0, 0.0001280.98, 90.24, 0.002202.05, 89.72, 0.02122.31, 62.65, 0.05617.78, 134.68, <0.0001
Female infants***−51.7, 55.68, 0.3567.36, 80.54, 0.40−172.47, 90.08, 0.06−137.68, 62.1, 0.03146.20, 111.10, 0.19
White Race****240.60, 63.07, 0.0002202.11, 46.26, <0.000135.21, 87.27, 0.68
High maternal BMI (≥30)201.68, 62.55, 0.001261.81, 82.95, 0.002161.64, 125.81, 0.2
Gestational age at delivery205.92, 23.84, <0.0001206.58, 35.92, <0.0001172.63, 37.79, <0.0001213.25, 24.9, <0.0001187.13, 54.47, 0.001
Smoking during
Pregnancy
−8.11, 31.02, 0.79−5.90, 47.40, 0.90−39.63, 47.26, 0.40−46.36, 33.28, 0.162.36, 68.16, 0.97
Delivery route151.57, 56.58, 0.008229.73, 84.34, 0.00874.06, 86.27, 0.40146.23, 62.58, 0.03178.73, 111.78, 0.11

Factors mutually adjusted for each other: IGF-I levels, infant gender, race, maternal BMI, maternal smoking, delivery route, and gestational age at delivery, to predict birth weight.
**Referents are individuals with lower (≤3rd Tertile) IGF-I at delivery.
***Referents are male infants.
****Referents are African Americans.
Referents are BMI < 30.
Referents are lower gestational age.
Referents are nonsmoking mothers.
Referents are vaginal delivery infants.