Probiotics and Prebiotics: Role in Prevention of Nosocomial Sepsis in Preterm Infants

Table 2

Meta-analyses of probiotics in neonates.

	Number of trials	Inclusion criteria	Number of infants	Sepsis (RR; 95% CI)	NEC (RR; 95% CI)	Mortality (RR; 95% CI)
Deshpande et al., 2007 [42]	7	<33 wks; <1500 g	1393	0.94; 0.74–1.20	0.36; 0.20–0.65	0.47; 0.30–0.73
Deshpande et al., 2010 [43]	11	<34 wks; <1500 g	2176	0.98; 0.81–1.18	0.35; 0.23–0.55	0.42; 0.29–0.62
Alfaleh et al., 2011 [44]	16	<37 wks; <2500 g	2842	0.90, 0.76–1.07	0.35, 0.24–0.52	0.40, 0.27–0.60
Wang et al., 2012 [46]	20	<34 wks; <1500 g	3816	0.90; 0.71–1.15	0.33; 0.24–0.46	0.56; 0.43–0.73