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International Journal of Pediatrics
Volume 2014, Article ID 149070, 6 pages
http://dx.doi.org/10.1155/2014/149070
Clinical Study

Abnormal Blood Glucose as a Prognostic Factor for Adverse Clinical Outcome in Children Admitted to the Paediatric Emergency Unit at Komfo Anokye Teaching Hospital, Kumasi, Ghana

1Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, Ghana
2Disease Control Unit, Ghana Health Service, Accra, Ghana
3Endocrinology and Diabetes Unit, British Columbia Children’s Hospital, Room K4-212, 4480 Oak Street, Vancouver, BC, Canada V6H 3V4

Received 17 August 2014; Revised 17 November 2014; Accepted 11 December 2014; Published 28 December 2014

Academic Editor: Stefan Burdach

Copyright © 2014 Emmanuel Ameyaw et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Dysglycaemia (hyper- or hypoglycaemia) in critically ill children has been associated with poor outcome. We compared the clinical outcomes in children admitted to Pediatric Emergency Unit (PEU) at Komfo Anokye Teaching Hospital (KATH) for acute medical conditions and presenting with euglycaemia or dysglycaemia. This is a prospective case matching cohort study. Eight hundred subjects aged between 3 and 144 months were screened out of whom 430 (215 with euglycaemia and 215 with dysglycaemia) were enrolled. The median age was 24 months (range: 3–144 months). In the dysglycaemia group, 28 (13%) subjects had hypoglycemia and 187 (87%) had hyperglycemia. Overall, there were 128 complications in 116 subjects. The number of subjects with complications was significantly higher in dysglycaemia group (, 46%) compared to euglycaemia group (, 8%) (). Forty subjects died out of whom 30 had dysglycaemia (). Subjects with dysglycaemia were 3 times (95% CI: 1.5–6.0) more likely to die and 4.8 times (95% CI: 3.1–7.5) more likely to develop complications (). Dysglycaemia is associated with increased morbidity and mortality in children with acute medical conditions and should lead to intensive management of the underlying condition.