TY - JOUR
A2 - Hutchinson, Raymond J.
AU - Wu, Grace
AU - Wollen, Alec
AU - DiBlasi, Robert M.
AU - Himley, Stephen
AU - Saxon, Eugene
AU - Austin, Glenn
AU - Delarosa, Jaclyn
AU - Izadnegahdar, Rasa
AU - Ginsburg, Amy Sarah
AU - Zehrung, Darin
PY - 2016
DA - 2016/11/23
TI - Reservoir Cannulas for Pediatric Oxygen Therapy: A Proof-of-Concept Study
SP - 9214389
VL - 2016
AB - Hypoxemia is a complication of pneumonia—the leading infectious cause of death in children worldwide. Treatment generally requires oxygen-enriched air, but access in low-resource settings is expensive and unreliable. We explored use of reservoir cannulas (RCs), which yield oxygen savings in adults but have not been examined in children. Toddler, small child, and adolescent breathing profiles were simulated with artificial lung and airway models. An oxygen concentrator provided flow rates of 0 to 5 L/min via a standard nasal cannula (NC) or RC, and delivered oxygen fraction (FdO2) was measured. The oxygen savings ratio (SR) and absolute flow savings (AFS) were calculated, comparing NC and RC. We demonstrated proof-of-concept that pendant RCs could conserve oxygen during pediatric therapy. SR mean and standard deviation were 1.1±0.2 to 1.4±0.4, 1.1±0.1 to 1.7±0.3, and 1.3±0.1 to 2.4±0.3 for toddler, small child, and adolescent models, respectively. Maximum AFS observed were 0.3±0.3, 0.2±0.1, and 1.4±0.3 L/min for the same models. RCs have the potential to reduce oxygen consumption during treatment of hypoxemia in children; however, further evaluation of products is needed, followed by clinical analysis in patients.
SN - 1687-9740
UR - https://doi.org/10.1155/2016/9214389
DO - 10.1155/2016/9214389
JF - International Journal of Pediatrics
PB - Hindawi Publishing Corporation
KW -
ER -