Morbidity and Mortality in Preterm Infants following Antacid Use: A Retrospective Audit

Table 2

Hospital factors in unexposed and exposed medication groups.

Hospital factor	Unexposed to ranitidine/omeprazole; ()	Exposed to ranitidine/omeprazole; ()	p value
Mean length of hospital stay (days) + SD	42.1 ± 31	74.7 ± 50.5	<0.001
Umbilical line access, % ()	83.4 (247)	93.8 (60)	0.055
PICC access, % ()	50.3(149)	70.3 (45)	0.006
Mean duration of umbilical line (days) + SD	6.5 ± 5.1	8.1 ± 4.7	0.028
Mean duration of PICC line (days) + SD	6.7 ± 13.1	11.5 ±14.3	0.01
Mechanical ventilation, % ()	63.5 (188)	79.7 (51)	<0.023
Mean duration of mechanical ventilation (days) + SD	5.1 ± 10.4	4.2 ± 11.3	0.563
CPAP, % ()	83.8 (248)	96.9 (62)	0.014
Mean duration of CPAP (days) + SD	14.9 ± 21.1	21.9 ± 15	0.013
Feeding type, % ()
EBM	46 (136)	42.2 (27)	0.242
Formula	2.7 (8)	1.6 (1)
Both	47 (139)	56.3 (36)
Nil	4.4 (13)	0 (0)
Time to full feeds (days) + SD	13.3 ± 9.6	15.4 ± 7.3	0.11