Can a Risk Factor Based Approach Safely Reduce Screening for Retinopathy of Prematurity?

Table 2

Combined logistic regression coefficients for infants with severe retinopathy of prematurity (ROP) or laser surgery.

	Severe ROP	value	Laser surgery	value
	()		()
	Odds ratio (95% CI)		Odds ratio (95% CI)
GA ≤ 24 weeks	49.4 (22.1–110.6)	<0.001	33.9 (18.7–364.6)	<0.001
GA 25 weeks	25.5 (11.6–56.1)	<0.001	25.0 (10.0–196.4)	<0.001
GA 26 weeks	22.5 (10.6–48.0)	<0.001	26.9 (11.1–206.7)	<0.001
GA 27 weeks	6.5 (3.0–14.9)	<0.001	11.7 (23.1–63.5)	0.01
GA 28 weeks	4.0 (1.7–9.4)	0.002	6.4 (1.6–39.8)	0.002
NEC surgery	2.9 (1.1–4.8)	0.038	8.8 (1.5–6.7)	0.003
Ventilator	(1.01–1.03)	<0.001	(1.01–1.02)	0.001
Inhaled nitric oxide	1.6 (1.1–2.4)	0.014	1.6 (1.01–2.5)	0.046
Sepsis	1.8 (1.1–3.1)	0.019	7.0 (2.1–23.2)	0.001
PDA surgery	1.6 (1.1–2.3)	0.011	1.8 (1.1–2.7)	0.011

in OR for each additional ventilator day. GA: gestational age; CI: confidence interval; NEC: necrotizing enterocolitis; PDA: patent ductus arteriosus.