Ghrelin, Des-Acyl Ghrelin, and Obestatin: Regulatory Roles on the Gastrointestinal Motility
Figure 1
Localization of ghrelin, des-acyl ghrelin and obestatin in the rat stomach. (a) Immunofluorescence double staining for acyl ghrelin- (red) and des-acyl ghrelin-positive (green) reaction in the antral mucosa of rat stomach. Acyl ghrelin-positive reaction and des-acyl ghrelin-positive reaction are colocalized in closed-type cells (arrows), whereas des-acyl ghrelin-positive reaction is localized in open-type cells (arrowheads). (b) Immunofluorescence triple staining for des-acyl ghrelin (green), acyl ghrelin (red) and obestatin (blue) in the antral mucosa of rat stomach. Three peptides are colocalized in the closed-type cells (arrows). Bars = 10 m.
