Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat

Table 1

Sequences of peptides examined. Peptide sequences are shown relative to the primary amino acid sequence of the Tat peptide. Position numbers are derived from the full-length Tat protein amino acid sequence (HIV-1 strain SF2) [21].

Peptide	Sequence										Charge
Tat peptide	G	R	K	K	R	R	Q	R	R	R	+8
TPvar1	R	—	—	—	—	—	—	—	—	—	+9
TPvar2	—	—	—	—	—	—	R	—	—	—	+9
TPvar3	R	—	—	—	—	—	R	—	—	—	+10
R-10	R	—	R	R	—	—	R	—	—	—	+10
aa position	48	49	50	51	52	53	54	55	56	57