Research Article

Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat

Table 2

Viral titer does not affect the antiviral activity of Tat peptide. EC50 values were calculated from the results of antiviral assays (as described in Section 2) involving infection by HIV-1 IIIB at three different multiplicities of infection (MOI).

Virus concentration during infection (103 infectious virions/mL)MOIEC50

880.60.094 mg/mL
8.80.050.14 mg/mL
4.40.030.10 mg/mL