Characterization of Selective Antibacterial Peptides by Polarity Index

Table 2

SCAAP subjects [7]. IP: estimated isoelectric point. HM: hydrophobic moment. TI: calculated therapeutic index. Peptides Cecropin-A and CA(1-8)M(1-18)NH2 were used to determine the P[𝑖,𝑗] incidence matrix.

Entry	Peptide	Sequence	IP	HM	TI
1	(KIAKKIA)2NH2	KIAKKIAKIAKKIA	11.5	0.48	86.2
2	(KLGKKLG)3NH2	KLGKKLGKLGKKLGKLGKKLG	11.7	0.49	98.3
3	Cecropin-A	KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK	11.2	0.44	1000.0
4	Melittin	GIGAVLKVLTTGLPALISWIKRKRQQ	12.6	0.46	500.0
5	Magainin 2	GIGKFLHSAKKFGKAFVGEIMNS	10.8	0.56	75.0
6	CA(1-13)M(1-13)NH2	KWKLFKKIEKVGQGIGAVLKVLTTGL	11.1	0.53	400.0
7	CA(1-8)M(1-18)NH2	KWKLFKKIGIGAVLKVLTTGLPALIS	10.4	0.43	2000.0