International Journal of Peptides / 2016 / Article / Tab 1

Research Article

Netrin-1 Peptide Is a Chemorepellent in Tetrahymena thermophila

Table 1

Cells that adapted to netrin-1 peptide are not cross-adapted to nociceptin, GTP, or PACAP-38. Percentage of avoidance, as listed below, represents the mean ± standard deviation of at least 6 trials. Each trial consisted of 10 cells which were individually observed and scored for avoidance within the first 5 seconds of exposure to the chemorepellent being tested. Adaptation to the same signal (e.g., GTP adapted to GTP, nociceptin adapted to nociceptin) was run as controls. Each of these controls showed adaptation, showing less than the baseline avoidance of 20% typically seen in behavioral assays.

GTPPACAP-38NociceptinNetrin-1 peptide

GTP13.3 ± 5.895.0 ± 5.094.0 ± 5.293.0 ± 4.1
PACAP96.6 ± 5.212.5 ± 9.697.5 ± 4.695.0 ± 5.5
Nociceptin96.6 ± 5.8100 ± 0.09.2 ± 8.295.0 ± 5.0
Netrin-1 peptide90.0 ± 10.090.0 ± 0.093.3 ± 5.86.66 ± 5.8

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