Peptide Inhibitor of Complement C1 Inhibits the Peroxidase Activity of Hemoglobin and Myoglobin

Figure 3

Comparison of PIC1 and ABAH inhibition of peroxidase activity of Hb from RBC lysates using ABTS and O-dianisidine as substrates. RBC lysates (1.25 × 10⁸ cells/ml equivalents) were incubated with increasing concentrations of PIC1 or ABAH. Samples were then combined with (a) ABTS or (b) O-dianisidine and absorbance was read at 405 nm. Data are means of three independent experiments ± SEM.

(a)

(b)