Table of Contents
International Journal of Plant Genomics
Volume 2008, Article ID 391259, 8 pages
Research Article

Conserved Microsynteny of NPR1 with Genes Encoding a Signal Calmodulin-Binding Protein and a CK1-Class Protein Kinase in Beta vulgaris and Two Other Eudicots

Molecular Plant Pathology Laboratory, Agricultural Research Service, United States Department of Agriculture, 10300 Baltimore Avenue, Building 004, Room 120, Beltsville, MD 20705, USA

Received 8 January 2008; Accepted 19 August 2008

Academic Editor: Silvana Grandillo

Copyright © 2008 David Kuykendall et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


NPR1 is a gene of central importance in enabling plants to resist microbial attack. Therefore, knowledge of nearby genes is important for genome analysis and possibly for improving disease resistance. In this study, systematic DNA sequence analysis, gene annotation, and protein BLASTs were performed to determine genes near the NPR1 gene in Beta vulgaris L., Medicago truncatula Gaertn, and Populus trichocarpa Torr. & Gray, and to access predicted function. Microsynteny was discovered for NPR1 with genes CaMP, encoding a chloroplast-targeted signal calmodulin-binding protein, and CK1PK, a CK1-class protein kinase. Conserved microsynteny of NPR1, CaMP, and CK1PK in three diverse species of eudicots suggests maintenance during evolution by positive selection for close proximity. Perhaps close physical linkage contributes to coordinated expression of these particular genes that may control critically important processes including nuclear events and signal transduction.