Table of Contents
International Journal of Plant Genomics
Volume 2012, Article ID 728398, 11 pages
http://dx.doi.org/10.1155/2012/728398
Review Article

SNP Markers and Their Impact on Plant Breeding

1Department of Trait Genetics and Technologies, Dow AgroSciences LLC, 9330 Zionsville Road, Indianapolis, IN 46268, USA
2Department of Biotechnology Regulatory Sciences, Dow AgroSciences LLC, 9330 Zionsville Road, Indianapolis, IN 46268, USA

Received 3 August 2012; Accepted 14 November 2012

Academic Editor: Ian Bancroft

Copyright © 2012 Jafar Mammadov et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The use of molecular markers has revolutionized the pace and precision of plant genetic analysis which in turn facilitated the implementation of molecular breeding of crops. The last three decades have seen tremendous advances in the evolution of marker systems and the respective detection platforms. Markers based on single nucleotide polymorphisms (SNPs) have rapidly gained the center stage of molecular genetics during the recent years due to their abundance in the genomes and their amenability for high-throughput detection formats and platforms. Computational approaches dominate SNP discovery methods due to the ever-increasing sequence information in public databases; however, complex genomes pose special challenges in the identification of informative SNPs warranting alternative strategies in those crops. Many genotyping platforms and chemistries have become available making the use of SNPs even more attractive and efficient. This paper provides a review of historical and current efforts in the development, validation, and application of SNP markers in QTL/gene discovery and plant breeding by discussing key experimental strategies and cases exemplifying their impact.