Cathepsin D Expression in Colorectal Cancer: From Proteomic Discovery through Validation Using Western Blotting, Immunohistochemistry, and Tissue Microarrays
Table 3
Cox regression analysis of tumor characteristics with respect to cancer survival.
Variable
HR
95% CI
value
Histological type (mucinous versus nonmucinous)
1.230
0.328–4.611
0.759
Histological grade (high grade versus low grade)
0.551
0.209–1.448
0.229
Vascular invasion (positive versus negative)
0.751
0.325–1.735
0.503
Operation (emergency versus elective)
1.079
0.467–2.492
0.859
Perineural invasion (positive versus negative)
2.788
1.055–7.370
0.039
Stage (I, II, III, IV)
15.333
6.030–38.992
0.0001
Cathepsin D expression at MTB (strong, moderate, weak)
