Comparison of Heavy Labeled (SIL) Peptide versus SILAC Protein Internal Standards for LC-MS/MS Quantification of Hepatic Drug Transporters

Figure 4

Standard deviation (a to d) and expression (e to h) of OATP1B1, OATP1B3, OATP2B1, and P-gp in individual liver sample (mean of triplicates) as determined by SIL (open bars) or SILAC (filled bars) internal standard methods. The last bar represents the population mean value. The individual hepatic expression data using SIL method are from our previous publication [15].

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