Hypoxia Strongly Affects Mitochondrial Ribosomal Proteins and Translocases, as Shown by Quantitative Proteomics of HeLa Cells

Figure 2

Protein-protein interaction analysis using STRING. Nodes and edges are colored according to type of evidence; protein structures are sketched in the circles. Dark green: neighborhood; red: gene fusion; dark blue: cooccurrence; dark purple: coexpression; light purple: experiments; light blue/green: databases; light green: text-mining; light blue: homology. The gene names are matched to Uniprot accession numbers in Table S1. The backgrounds of up- and downregulated clusters are the shaded backgrounds in red and green, respectively (right: glycolysis, upregulated; bottom: mitochondrial translocases and left: mitochondrial ribosomal proteins, both downregulated).