International Journal of Proteomics

Proteomics-Based Disease Biomarkers


Publishing date
01 Dec 2011
Status
Published
Submission deadline
01 Jun 2011

Lead Editor

1Department of Surgery, University of Michigan, Ann Arbor, MI, 48109, USA

2Division of Pharmacoproteomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan

3Division of Endocrinology, Metabolism and Diabetes, School of Medicine, University of Colorado Denver, Aurora, CO 80045 , USA; Obesity Research Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia


Proteomics-Based Disease Biomarkers

Description

Sequencing of the human genome has greatly impacted the proteomics-based analysis of disease by providing a framework for understanding the proteome of diseased cells, tissues, and biological fluids. There is much interest in applying proteomics technologies to discover processes at the protein level that are involved in various diseases, to uncover new biomarkers that correlate with the early diagnosis of diseases and to accelerate the development of new therapeutic targets. New proteomics technologies are being developed in order to facilitate both the high-throughput and high-sensitivity requirements of disease-related applications of proteomics. These innovative technologies have greatly enhanced our ability to separate and characterize complex protein mixtures. They have also aided our ability to identify proteins with greater sensitivity, thereby providing the groundwork for future scientific breakthroughs and possibly providing the framework for the development of personalized disease therapy.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand disease subtypes at the protein level, the development of protein-based biomarkers for the early detection of disease, the development of treatment modalities based upon disease-specific protein biomarker signatures, and the protein- biomarker-based evaluation of therapeutic efficacy. We are interested in articles that explore aspects of protein-based biomarkers in humans and also in animal models of disease. Potential topics include, but are not limited to:

  • Protein-based signatures of disease subtypes, with emphasis on the expression of different protein biomarkers reflective of a given disease subtype
  • Protein-based biomarkers for the early detection of diseases, including potential disease-specific posttranslational modifications of proteins
  • Latest technologies for the elucidation of protein signatures of disease, including autoantibodies
  • Role of protein biomarkers in the process of drug development
  • Role of protein biomarkers in the evaluation of therapeutic efficacy
  • Role of protein biomarkers in predicting and monitoring side effects of therapeutic intervention

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijpro/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 894618
  • - Editorial

Proteomics-Based Disease Biomarkers

David E. Misek | Tadashi Kondo | Mark W. Duncan
  • Special Issue
  • - Volume 2011
  • - Article ID 145010
  • - Research Article

Comprehensive Proteomic Profiling of Aldehyde Dehydrogenases in Lung Adenocarcinoma Cell Lines

Qing Zhang | Ayumu Taguchi | ... | Samir Hanash
  • Special Issue
  • - Volume 2011
  • - Article ID 896476
  • - Research Article

Proteomic-Based Biosignatures in Breast Cancer Classification and Prediction of Therapeutic Response

Jianbo He | Stephen A. Whelan | ... | Helena R. Chang
  • Special Issue
  • - Volume 2011
  • - Article ID 413646
  • - Review Article

The Use of Protein-Based Biomarkers for the Diagnosis of Cystic Tumors of the Pancreas

Richard S. Kwon | Diane M. Simeone
  • Special Issue
  • - Volume 2011
  • - Article ID 413742
  • - Research Article

Clinical Utility of Serum Autoantibodies Detected by Protein Microarray in Melanoma

Michael S. Sabel | Yashu Liu | ... | David M. Lubman
  • Special Issue
  • - Volume 2011
  • - Article ID 628787
  • - Research Article

The Application of a Three-Step Proteome Analysis for Identification of New Biomarkers of Pancreatic Cancer

Mayinuer Abulaizi | Takeshi Tomonaga | ... | Fumio Nomura
  • Special Issue
  • - Volume 2011
  • - Article ID 181890
  • - Review Article

Proteomics in Melanoma Biomarker Discovery: Great Potential, Many Obstacles

Michael S. Sabel | Yashu Liu | David M. Lubman
  • Special Issue
  • - Volume 2011
  • - Article ID 214715
  • - Research Article

Urine Glycoprotein Profile Reveals Novel Markers for Chronic Kidney Disease

Anuradha Vivekanandan-Giri | Jessica L. Slocum | ... | Subramaniam Pennathur
  • Special Issue
  • - Volume 2011
  • - Article ID 601937
  • - Review Article

Glycoproteomics-Based Identification of Cancer Biomarkers

Evelyn H. Kim | David E. Misek
  • Special Issue
  • - Volume 2011
  • - Article ID 502845
  • - Research Article

Adsorption of Urinary Proteins on the Conventionally Used Urine Collection Tubes: Possible Effects on Urinary Proteome Analysis and Prevention of the Adsorption by Polymer Coating

Iwao Kiyokawa | Kazuyuki Sogawa | ... | Fumio Nomura

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