Enzyme-Mediated Ring-Opening Polymerization of Pentadecalactone to Obtain Biodegradable Polymer for Fabrication of Scaffolds for Bone Tissue Engineering

Table 6

Effects of polymer yield, reaction time, and product intrinsic viscosity on [M]/[HEMA].

Sample number	Time, h	[M]/[HEMA], mol/mol	Yield, %	[η], dL/g	𝑀𝑤×10^−3  (GPC)	𝑀𝑤/𝑀𝑛 *
22	5	Control	87	0.58	26.7	1.43
23	5	20	85	0.21	16.4	1.56
24	5	40	88	0.32	22.0	1.63

Reaction conditions: T = 55°C, [M]/[E]—30 wt./wt., [M]—25 wt.%.
∗The ratio is given for macromolecular peak only, while for the whole sample, the PDI is much higher.