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International Journal of Polymer Science
Volume 2014 (2014), Article ID 579252, 6 pages
Research Article

The Development of Biomimetic Spherical Hydroxyapatite/Polyamide 66 Biocomposites as Bone Repair Materials

1Department of Orthopaedics, Chinese People’s Liberation Army General Hospital, Beijing 100853, China
2Department of Endocrinology, China-Japan Friendship Hospital, Beijing 100029, China

Received 28 February 2014; Accepted 21 May 2014; Published 6 July 2014

Academic Editor: Xiaoming Li

Copyright © 2014 Xuesong Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A novel biomedical material composed of spherical hydroxyapatite (s-HA) and polyamide 66 (PA) biocomposite (s-HA/PA) was prepared, and its composition, mechanical properties, and cytocompatibility were characterized and evaluated. The results showed that HA distributed uniformly in the s-HA/PA matrix. Strong molecule interactions and chemical bonds were presented between the s-HA and PA in the composites confirmed by IR and XRD. The composite had excellent compressive strength in the range between 95 and 132 MPa, close to that of natural bone. In vitro experiments showed the s-HA/PA composite could improve cell growth, proliferation, and differentiation. Therefore, the developed s-HA/PA composites in this study might be used for tissue engineering and bone repair.