Research Article
Evaluation of Microcrystalline Chitosan and Fibrin Membranes as Platelet-Derived Growth Factor-BB Carriers with Amoxicillin
Table 2
Constant values of kinetic equation describing in vitro PDGF-BB release from the membranes, mean ± SD.
| Type of membranes | Phase I | Phase II | | (%) | (h−1) | (h) | (%) | (h−1) | (h) |
| M1 | 2.43 ± 0.11 | 0.476 ± 0.086 | 1.46 | 4.45 ± 0.10 | 13.0 ± 0.76 | 53.3 | 0.9998 | M1′ | 2.01 ± 0.07 | 0.416 ± 0.047 | 1.67 | 4.57 ± 0.06 | 13.9 ± 4.82 | 49.9 | 0.9999 | M2 | 5.20 ± 0.11 | 0.792 ± 0.217 | 0.88 | 2.26 ± 0.11 | 10.4 ± 1.5 | 66.6 | 0.9998 | M2′ | 4.56 ± 0.08 | 0.743 ± 0.128 | 0.93 | 2.30 ± 0.19 | 5.86 ± 1.29 | 118 | 0.9999 | M3 | 0.244 ± 0.020 | 0.212 ± 0.045 | 3.27 | 1.20 ± 0.068 | 3.24 ± 0.043 | 214 | 0.9994 | M3′ | 0.572 ± 0.020 | 0.0240 ± 0.0076 | 28.9 | 0.146 ± 0.014 | 3.00 ± 0.15 | 231 | 0.9973 | M4 | 0.317 ± 0.035 | 0.174 ± 0.044 | 3.98 | 1.24 ± 0.038 | 5.50 ± 0.060 | 126 | 0.9992 | M4′ | 0.352 ± 0.015 | 0.0378 ± 0.0014 | 18.3 | 0.518 ± 0.013 | 7.57 ± 0.29 | 91.5 | 0.9991 | M5 | 0.132 ± 0.009 | 0.250 ± 0.045 | 2.77 | 0.650 ± 0.014 | 4.79 ± 0.321 | 145 | 0.9997 | M5′ | 0.309 ± 0.022 | 0.259 ± 0.041 | 2.66 | 0.468 ± 0.020 | 11.2 ± 1.10 | 61.9 | 0.9993 |
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