Table of Contents Author Guidelines Submit a Manuscript
International Journal of Polymer Science
Volume 2015, Article ID 535092, 9 pages
http://dx.doi.org/10.1155/2015/535092
Research Article

Development of a Layer-by-Layer Assembled Film on Hydrogel for Ocular Drug Delivery

School of Material Engineering, Jinling Institute of Technology, Nanjing 211169, China

Received 5 November 2014; Accepted 8 December 2014

Academic Editor: Yen-Chih Lin

Copyright © 2015 Pin Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. Liu, M. Griffith, and F. Li, “Alginate microsphere-collagen composite hydrogel for ocular drug delivery and implantation,” Journal of Materials Science: Materials in Medicine, vol. 19, no. 11, pp. 3365–3371, 2008. View at Publisher · View at Google Scholar
  2. X. Chen, X. Li, Y. Zhou et al., “Chitosan-based thermosensitive hydrogel as a promising ocular drug delivery system: preparation, characterization, and in vivo evaluation,” Journal of Biomaterials Applications, vol. 27, no. 4, pp. 391–402, 2012. View at Publisher · View at Google Scholar
  3. C. Lu, R. B. Yoganathan, M. Kociolek, and C. Allen, “Hydrogel containing silica shell cross-linked micelles for ocular drug delivery,” Journal of Pharmaceutical Sciences, vol. 102, no. 2, pp. 627–637, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. J. Yu, X. Xu, F. Yao et al., “In situ covalently cross-linked PEG hydrogel for ocular drug delivery applications,” International Journal of Pharmaceutics, vol. 470, no. 1-2, pp. 151–157, 2014. View at Publisher · View at Google Scholar
  5. C. Lu, X. Wang, G. Wu et al., “An injectable and biodegradable hydrogel based on poly(α,β-aspartic acid) derivatives for localized drug delivery,” Journal of Biomedical Materials Research Part A, vol. 102, no. 3, pp. 628–638, 2014. View at Publisher · View at Google Scholar
  6. G. R. Bardajee and Z. Hooshyar, “One-pot synthesis of biocompatible superparamagnetic iron oxide nanoparticles/hydrogel based on salep: characterization and drug delivery,” Carbohydrate Polymers, vol. 101, no. 1, pp. 741–751, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Jiang, J. Sun, and F. Ding, “PEG-g-chitosan thermosensitive hydrogel for implant drug delivery: cytotoxicity, in vivo degradation and drug release,” Journal of Biomaterials Science, Polymer Edition, vol. 25, no. 3, pp. 241–256, 2014. View at Publisher · View at Google Scholar
  8. C.-C. Peng and A. Chauhan, “Extended cyclosporine delivery by silicone-hydrogel contact lenses,” Journal of Controlled Release, vol. 154, no. 3, pp. 267–274, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. H. J. Jung, M. Abou-Jaoude, B. E. Carbia, C. Plummer, and A. Chauhan, “Glaucoma therapy by extended release of timolol from nanoparticle loaded silicone-hydrogel contact lenses,” Journal of Controlled Release, vol. 165, no. 1, pp. 82–89, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. L. C. Bengani, J. Leclerc, and A. Chauhan, “Lysozyme transport in p-HEMA hydrogel contact lenses,” Journal of Colloid and Interface Science, vol. 386, no. 1, pp. 441–450, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Robitaille, J. Shi, S. McBride, and K. T. Wan, “Mechanical performance of hydrogel contact lenses with a range of power under parallel plate compression and central load,” Journal of the Mechanical Behavior of Biomedical, vol. 2, pp. 259–264, 2013. View at Google Scholar
  12. M. Bettuelli, S. Trabattoni, M. Fagnola, S. Tavazzi, L. Introzzi, and S. Farris, “Surface properties and wear performances of siloxane-hydrogel contact lenses,” Journal of Biomedical Materials Research. Part B Applied Biomaterials, vol. 101, no. 8, pp. 1585–1593, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. X. H. Hu and D. Li, “Facile way to synthesise hydrogel contact lenses with good performance for ophthalmic drug delivery,” Materials Technology, vol. 28, no. 4, pp. 192–198, 2013. View at Publisher · View at Google Scholar
  14. X. H. Hu, X. X. Chen, H. P. Tan, D. Li, Y. S. Zhang, and C. B. Pan, “Preparation of biocompatible graphene oxide composite hydrogel to deliver ophthalmic drugs,” Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, vol. 50, no. 12, pp. 1201–1208, 2013. View at Publisher · View at Google Scholar
  15. X. H. Hu, J. Qiu, H. P. Tan, D. Li, and X. H. Ma, “Synthesis and characterization of cyclodextrin-containing hydrogel for ophthalmic drugs delivery,” Journal of Macromolecular Science, Part A, vol. 50, pp. 983–990, 2013. View at Publisher · View at Google Scholar
  16. A. E. El Haitami, J.-S. Thomann, L. Jierry et al., “Covalent layer-by-layer assemblies of polyelectrolytes and homobifunctional spacers,” Langmuir, vol. 26, no. 14, pp. 12351–12357, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Gill, M. Mazhar, O. Felix, and G. Decher, “Covalent layer-by-layer assembly and solvent memory of multilayer films from homobifunctional poly(dimethylsiloxane),” Angewandte Chemie International Edition, vol. 49, no. 35, pp. 6116–6119, 2010. View at Publisher · View at Google Scholar
  18. Z. Zhao, L. Yin, G. Yuan, and L. Wang, “Layer-by-layer assembly of two temperature-responsive homopolymers at neutral pH and the temperature-dependent solubility of the multilayer film,” Langmuir, vol. 28, no. 5, pp. 2704–2709, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Guo, W. Geng, and J. Sun, “Layer-by-layer deposition of polyelectrolyte-polyelectrolyte complexes for multilayer film fabrication,” Langmuir, vol. 25, no. 2, pp. 1004–1010, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. Q. Tang, J. Wu, X. Sun, Q. Li, and J. Lin, “Layer-by-layer self-assembly of conducting multilayer film from poly(sodium styrenesulfonate) and polyaniline,” Journal of Colloid and Interface Science, vol. 337, no. 1, pp. 155–161, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. D.-G. Yu, W.-C. Lin, and M.-C. Yang, “Surface modification of poly(L-lactic acid) membrane via layer-by-layer assembly of silver nanoparticle-embedded polyelectrolyte multilayer,” Bioconjugate Chemistry, vol. 18, no. 5, pp. 1521–1529, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. X. H. Hu, H. P. Tan, D. Li, and M. Y. Gu, “Surface functionalisation of contact lenses by CS/HA multilayer film to improve its properties and deliver drugs,” Materials Technology, vol. 29, no. 1, pp. 8–13, 2014. View at Publisher · View at Google Scholar
  23. T. R. Thatiparti and H. A. von Recum, “Cyclodextrin complexation for affinity-based antibiotic delivery,” Macromolecular Bioscience, vol. 10, no. 1, pp. 82–90, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. T. R. Thatiparti, A. J. Shoffstall, and H. A. von Recum, “Cyclodextrin-based device coatings for affinity-based release of antibiotics,” Biomaterials, vol. 31, no. 8, pp. 2335–2347, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Chen, W.-L. Lu, W. Gu et al., “Drug-in-cyclodextrin-in-liposomes: a promising delivery system for hydrophobic drugs,” Expert Opinion on Drug Delivery, vol. 11, no. 4, pp. 565–577, 2014. View at Publisher · View at Google Scholar
  26. R. J. Glisoni, M. J. García-Fernández, M. Pino et al., “β-Cyclodextrin hydrogels for the ocular release of antibacterial thiosemicarbazones,” Carbohydrate Polymers, vol. 93, no. 2, pp. 449–457, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Xu, X. Li, and F. Sun, “Cyclodextrin-containing hydrogels for contact lenses as a platform for drug incorporation and release,” Acta Biomaterialia, vol. 6, no. 2, pp. 486–493, 2010. View at Publisher · View at Google Scholar
  28. J.-F. Rosa dos Santos, C. Alvarez-Lorenzo, M. Silva et al., “Soft contact lenses functionalized with pendant cyclodextrins for controlled drug delivery,” Biomaterials, vol. 30, no. 7, pp. 1348–1355, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. X. Gong, J. Yang, L. Han, and C. Gao, “Influence of drying time of polyelectrolyte multilayers on the compression-induced pattern formation,” Langmuir, vol. 24, no. 24, pp. 13925–13933, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. X. Gong, L. Han, Y. Yue, J. Gao, and C. Gao, “Influence of assembly pH on compression and Ag nanoparticle synthesis of polyelectrolyte multilayers,” Journal of Colloid and Interface Science, vol. 355, no. 2, pp. 368–373, 2011. View at Publisher · View at Google Scholar · View at Scopus
  31. X. Gong, L. Han, J. Gao, and C. Gao, “Stability of polyelectrolyte multilayer micropatterns in response to post-treatments,” Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol. 396, pp. 299–304, 2012. View at Publisher · View at Google Scholar · View at Scopus
  32. X. Gong and C. Gao, “Influence of salt on assembly and compression of PDADMAC/PSSMA polyelectrolyte multilayers,” Physical Chemistry Chemical Physics, vol. 11, no. 48, pp. 11577–11586, 2009. View at Publisher · View at Google Scholar · View at Scopus