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International Journal of Polymer Science
Volume 2016, Article ID 5614687, 6 pages
http://dx.doi.org/10.1155/2016/5614687
Research Article

Effect of Sodium Salicylate on the Viscoelastic Properties and Stability of Polyacrylate-Based Hydrogels for Medical Applications

Centre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Trida T. Bati 5678, 76001 Zlín, Czech Republic

Received 13 December 2015; Revised 19 January 2016; Accepted 31 January 2016

Academic Editor: Yakai Feng

Copyright © 2016 Zuzana Kolarova Raskova et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Investigation was made into the effect exerted by the presence of sodium salicylate (0–2 wt.%), in Carbomer-based hydrogel systems, on processing conditions, rheological and antimicrobial properties in tests against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial strains, and examples of yeast (Candida albicans) and mould (Aspergillus niger). In addition, the work presents an examination of long-term stability by means of aging over one year the given hydrogels at 8°C and 25°C. The results show that 0.5 wt.% NaSal demonstrated a noticeable effect on the hydrogel neutralization process, viscosity, and antimicrobial properties against all of the tested microorganisms. The long-term stability studies revealed that hydrogels can maintain antimicrobial activity as well as viscosity to a degree that would be sufficient for practical use.