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International Journal of Polymer Science
Volume 2016, Article ID 8458752, 5 pages
Research Article

Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction

School of Ophthalmology & Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China

Received 5 May 2016; Accepted 26 May 2016

Academic Editor: Weifeng Zhao

Copyright © 2016 Junmei Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Poly(dimethylsiloxane) silicones have found many applications in biomedical devices, whereas their surface hydrophobicity always brings about unexpected bioadhesion, causing complications of the implanted biomedical devices. In this work, surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization was utilized to generate PEG brushes on silicone surface, obtaining highly hydrophilic surface coatings. Such PEG brush coated silicone presents excellent antifouling to protein, cells, and bacteria, which may have great potential in implantable biomaterial surface modifications.