Research Article

Influence of Hydrophilic Polymers on the Factor in Weibull Equation Applied to the Release Kinetics of a Biologically Active Complex of Aesculus hippocastanum

Table 2

Kinetic models applied for evaluation of obtained data.

Applied modelGeneral equationParameters

Zero-order
1st-order
2nd-order
Weibull

is rate constant, respectively, for zero-order kinetics (), 1st-order kinetics (), 2nd-order kinetics (), and Higuchi model (); , time; , half release time; , initial percentage of the released drug; , percentage of the released drug after time ; , time after release of 63.2% of drug from the formulation; , a shape parameter in the Weibull model; , , slope and intersection of the graph representing the release process.