Research Article

Biocompatibility Assessment of Poly(lactic acid) Films after Sterilization with Ethylene Oxide in Histological Study In Vivo with Wistar Rats and Cellular Adhesion of Fibroblasts In Vitro

Table 2

Results of histological analysis of surface tissue for the three periods of exposure.

Without inflammation Mild inflammation
Number of rats Number of rats
(%)(%)

Superficial tissue
 With polymer2 (40)3 (60)
 Without polymer5 (100)0 (0)
Deep tissue
 With polymer2 (40)3 (60)
 Without polymer5 (100)0 (0)
Days after surgery
(left dorsal area)
 143 (75)1 (25)
 212 (50)2 (50)
 281 (50)1 (50)