Identification of a Novel Anticancer Oligopeptide from Perilla frutescens (L.) Britt. and Its Enhanced Anticancer Effect by Targeted Nanoparticles In Vitro

Figure 5

Cytotoxicity of HA/PSO/C NPs on various cancer cells. Anticancer effect of HA/PSO/C NPs or free PSO on U251, A549, HCT116, HepG2, and MGC-803 with 1 mg/ml for 24 h, measured by the MTT assay. Percentages of cell proliferation were normalized by optical density values of the vehicle group (as 100%). Data are shown as means ± SD (). denotes , and denotes ; comparisons were performed between groups of HA/PSO/C NPs and PSO. # denotes ## denotes , and ### denotes ; comparisons were performed against the vehicle group.