Manufacture and Characterization of Mucoadhesive Buccal Films Based on Pectin and Gellan Gum Containing Triamcinolone Acetonide

Table 2

Properties of buccal films (mean ± SD, ): percentage of swelling (%), drug content (%), thickness (mm), force (N), puncture strength (N/mm²), elongation break (%), and mucoadhesive strength (N/cm²).

Film	Swelling	Drug content	Thickness	Force	Puncture strength	Elongation to break	Mucoadhesive strength
	%	Q%	mm	N	N/mm^2	%	N/cm^2
F1	320.53 ± 1.08	109.60 ± 1.80	0.119 ± 0.016	12.58 ± 0.11	0.69 ± 0.006	25.53 ± 5.53	3.49 ± 0.05
F2	298.93 ± 0.53	103.60 ± 4.19	0.148 ± 0.015	10.66 ± 3.24	0.59 ± 0.179	35.98 ± 2.42	3.68 ± 0.03
F3	442.11 ± 2.73	110.90 ± 0.13	0.166 ± 0.012	26.35 ± 9.38	1.45 ± 0.518	42.15 ± 2.05	5.30 ± 0.07
F4	438.99 ± 1.74	109.30 ± 0.22	0.242 ± 0.018	21.07 ± 1.99	1.16 ± 0.110	49.68 ± 9.11	5.50 ± 0.06
F5	482.99 ± 9.04	97.37 ± 1.85	0.205 ± 0.029	31.79 ± 2.95	1.75 ± 0.162	39.59 ± 5.01	5.47 ± 0.11
F6	480.12 ± 7.37	103.37 ± 1.25	0.225 ± 0.025	21.17 ± 3.30	1.39 ± 0.182	40.93 ± 2.06	5.74 ± 0.06
F7	540.99 ± 3.35	102.01 ± 0.55	0.233 ± 0.027	48.57 ± 12.79	2.68 ± 0.707	31.78 ± 10.14	7.31 ± 0.07
F8	572.70 ± 2.16	103.94 ± 1.90	0.222 ± 0.021	48.07 ± 13.13	2.66 ± 0.725	44.00 ± 13.15	7.57 ± 0.07