Study on the Role of the Inclusion Complexes with 2-Hydroxypropyl-β-cyclodextrin for Oral Administration of Amiodarone

Table 6

Drug release parameters of the inclusion complexes (AMD/HP-β-CD A, AMD/HP-β-CD B, and AMD/HP-β-CD C) and pure AMD.

Release characteristic	pH 1.2				pH 6.8
	A	B	C	AMD	A	B	C	AMD
(%)	79.3	83.2	72.1	6.2	88.1	89.3	85.6	7.6
(min)	177.6	169.3	191.2	40.3	138.8	136.5	140.8	4.4

: maximum release amount; : half release time.