Novel Nanoparticle Biomaterial of Alginate/Chitosan Loading Simultaneously Lovastatin and Ginsenoside RB1: Characteristics, Morphology, and Drug Release Study

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Sample</td><td class="align_center" colspan="5">Wavenumber (cm<sup>-1</sup>)</td></tr><tr class="thead"><td class="align_center"><span style="width: 40.656ptpx;"><svg height="9.45295pt" id="M15" style="vertical-align:-3.30936pt" version="1.1" viewbox="-0.0498162 -6.14359 40.656 9.45295" width="40.656pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M213 67C239 136 257 225 255 300C253 353 242 447 164 447C112 447 54 389 41 319L67 309C90 362 117 377 134 377C184 377 189 277 190 239C193 153 164 43 146 -12H176C278 73 450 253 450 390C450 439 410 463 396 463C384 463 380 459 382 449C385 440 389 415 389 402C389 284 312 146 216 67H213Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,5.902,3.132)"><path d="M719 650H483V622C553 619 576 606 581 560C585 532 588 487 588 394V148H585L167 650H20V622C67 618 88 610 109 585C127 562 129 557 129 484V264C129 173 126 124 123 93C118 44 92 31 35 28V0H272V28C204 32 181 44 176 95C173 124 170 172 170 264V515H172L598 -9H629V394C629 487 631 532 635 563C639 606 663 619 719 622V650Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,12.663,3.132)"><path d="M729 650H468V622C546 615 554 610 554 527V365H213V527C213 610 221 616 297 622V650H38V622C120 616 128 611 128 527V123C128 39 120 34 40 28V0H303V28C221 34 213 40 213 123V322H554V123C554 39 546 34 460 28V0H728V28C647 34 639 39 639 123V527C639 610 647 615 729 622V650Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,19.685,3.132)"><path d="M414 144C384 79 371 75 317 75H135L276 221C367 316 408 376 408 465C408 570 327 635 237 635C179 635 131 609 100 575L42 494L67 471C94 510 138 565 205 565C277 565 321 517 321 435C321 348 258 270 195 195C146 137 88 81 33 26V0H411C423 44 433 88 446 135L414 144Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,24.117,3.132)"><path d="M117 -12C153 -12 178 12 178 50C178 84 153 110 118 110C84 110 59 84 59 50C59 12 84 -12 117 -12Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,26.274,3.132)"><path d="M381 665C170 665 44 498 44 318C44 125 188 -15 369 -15C552 -15 703 117 703 333C703 534 550 665 381 665ZM359 629C491 629 601 517 601 306C601 114 502 21 390 21C249 21 146 158 146 346S248 629 359 629Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,32.989,3.132)"><path d="M729 650H468V622C546 615 554 610 554 527V365H213V527C213 610 221 616 297 622V650H38V622C120 616 128 611 128 527V123C128 39 120 34 40 28V0H303V28C221 34 213 40 213 123V322H554V123C554 39 546 34 460 28V0H728V28C647 34 639 39 639 123V527C639 610 647 615 729 622V650Z"></path></g></svg></span></td><td class="align_center"><span style="width: 19.5928ptpx;"><svg height="9.45295pt" id="M16" style="vertical-align:-3.30936pt" version="1.1" viewbox="-0.0498162 -6.14359 19.5928 9.45295" width="19.5928pt" 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-15C474 -15 558 5 586 11C604 45 629 119 643 165L614 175Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,11.976,3.132)"><path d="M556 331V384H55V331H556ZM556 140V193H55V140H556Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,17.536,3.132)"><path d="M381 665C170 665 44 498 44 318C44 125 188 -15 369 -15C552 -15 703 117 703 333C703 534 550 665 381 665ZM359 629C491 629 601 517 601 306C601 114 502 21 390 21C249 21 146 158 146 346S248 629 359 629Z"></path></g></svg></span></td><td class="align_center"><span style="width: 25.2494ptpx;"><svg height="12.5612pt" id="M18" style="vertical-align:-3.27287pt" version="1.1" viewbox="-0.0498162 -9.28833 25.2494 12.5612" width="25.2494pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M494 514C482 587 419 712 303 712C238 712 174 667 174 603C174 561 205 514 249 449C219 438 187 422 162 407C93 366 23 283 23 177C23 69 87 -12 190 -12C244 -12 288 5 328 33C406 87 444 170 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transform="matrix(.0091,0,0,-0.0091,20.179,3.132)"><path d="M414 144C384 79 371 75 317 75H135L276 221C367 316 408 376 408 465C408 570 327 635 237 635C179 635 131 609 100 575L42 494L67 471C94 510 138 565 205 565C277 565 321 517 321 435C321 348 258 270 195 195C146 137 88 81 33 26V0H411C423 44 433 88 446 135L414 144Z"></path></g></svg></span></td><td class="align_center"><span style="width: 36.6552ptpx;"><svg height="9.5443pt" id="M19" style="vertical-align:-3.40071pt" version="1.1" viewbox="-0.0498162 -6.14359 36.6552 9.5443" width="36.6552pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M213 67C239 136 257 225 255 300C253 353 242 447 164 447C112 447 54 389 41 319L67 309C90 362 117 377 134 377C184 377 189 277 190 239C193 153 164 43 146 -12H176C278 73 450 253 450 390C450 439 410 463 396 463C384 463 380 459 382 449C385 440 389 415 389 402C389 284 312 146 216 67H213Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,5.902,3.132)"><path d="M614 175C564 76 510 21 408 21C256 21 146 149 146 336C146 488 235 629 402 629C510 629 570 586 597 480L626 488C620 541 614 582 606 638C578 643 510 665 429 665C206 665 44 527 44 316C44 157 153 -15 402 -15C474 -15 558 5 586 11C604 45 629 119 643 165L614 175Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,11.976,3.132)"><path d="M556 236V289H56V236H556Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,17.536,3.132)"><path d="M381 665C170 665 44 498 44 318C44 125 188 -15 369 -15C552 -15 703 117 703 333C703 534 550 665 381 665ZM359 629C491 629 601 517 601 306C601 114 502 21 390 21C249 21 146 158 146 346S248 629 359 629Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,24.359,3.132)"><path d="M556 236V289H56V236H556Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,29.92,3.132)"><path d="M614 175C564 76 510 21 408 21C256 21 146 149 146 336C146 488 235 629 402 629C510 629 570 586 597 480L626 488C620 541 614 582 606 638C578 643 510 665 429 665C206 665 44 527 44 316C44 157 153 -15 402 -15C474 -15 558 5 586 11C604 45 629 119 643 165L614 175Z"></path></g></svg></span></td></tr><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr><td class="align_left">Alginat (AG)</td><td class="align_center">3448.16</td><td class="align_center">2923.65</td><td class="align_center">1626.64</td><td class="align_center">_</td><td class="align_center">1096.95</td></tr><tr><td class="align_left">Chitosan (CS)</td><td class="align_center">3447.62</td><td class="align_center">2883.51</td><td class="align_center">_</td><td class="align_center">1598.29</td><td class="align_center">1081</td></tr><tr><td class="align_left">Lovastatin (Lov)</td><td class="align_center">3640.99</td><td class="align_center">2966.06</td><td class="align_center">1728.11</td><td class="align_center">_</td><td class="align_center">1077.79</td></tr><tr><td class="align_left">Ginsenoside Rb1</td><td class="align_center">3423.35</td><td class="align_center">2941.92</td><td class="align_center">1077.79</td><td class="align_center">1451.91</td><td class="align_center">1070</td></tr><tr><td class="align_left">R5L0</td><td class="align_center">3451.51</td><td class="align_center">2928.31</td><td class="align_center">1627.43</td><td class="align_center">1414.17</td><td class="align_center">1089.41</td></tr><tr><td class="align_left">R0L10</td><td class="align_center">3443.16</td><td class="align_center">2928.37</td><td class="align_center">1621.10</td><td class="align_center">1416.30</td><td class="align_center">1090.57</td></tr><tr><td class="align_left">R3L10</td><td class="align_center">3440.53</td><td class="align_center">2931.39</td><td class="align_center">1619.98</td><td class="align_center">1415.55</td><td class="align_center">1033.70</td></tr><tr><td class="align_left">R5L10</td><td class="align_center">3426.96</td><td class="align_center">2931.39</td><td class="align_center">1616.12</td><td class="align_center">1415.55</td><td class="align_center">1091.56</td></tr><tr><td class="align_left">R5L20</td><td class="align_center">3441.66</td><td class="align_center">2968.62</td><td class="align_center">1628.84</td><td class="align_center">1535.36</td><td class="align_center">1075.37</td></tr><tr class="table-tr"><td colspan="6"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>IR band for characterized groups of AG, CS, Lov, ginsenoside Rb1, and NPB with different Lov content.</div>

International Journal of Polymer Science

tab3

Table 3

Table 3: Novel Nanoparticle Biomaterial of Alginate/Chitosan Loading Simultaneously Lovastatin and Ginsenoside RB1: Characteristics, Morphology, and Drug Release Study 

Table 3 | Novel Nanoparticle Biomaterial of Alginate/Chitosan Loading Simultaneously Lovastatin and Ginsenoside RB1: Characteristics, Morphology, and Drug Release Study 