Research Article

Momordica Charantia Polysaccharides Attenuates MPP+-Induced Injury in Parkinson’s Disease Mice and Cell Models by Regulating TLR4/MyD88/NF-κB Pathway

Figure 3

MCPs reduce the inflammation, oxidative stress, and apoptosis of PD induced by MPTP. (a, b) Expression of proinflammatory cytokines TNF-α and IL-1β in striatum tissue homogenate. (c–e) Expression of oxidative stress-related factors MDA, SOD, and GSH in striatum tissue homogenate. (f) The expression levels of oxidative stress-related protein Cytochrome C and apoptosis-related proteins Bcl-2, Bax, and cleaved Caspase-3 in striatal tissue homogenate. (g) Tyrosine hydroxylase (TH) protein level in striatum tissue homogenate. Compared with Control group (Control+MCPs group), , compared with PD group, ##, ###.