Biomaterials and medical devices normally induce a set of adverse biological responses upon implantation into living organs or getting into contact with body fluids. Functional polymers have been of interest recently because of their promising properties for improving the biocompatibility of the materials. Specifically, bioinert and bioactive polymers combined with modern fabrication technologies result in a variety of biofunctional materials with versatile surface effects, including antifouling, antibacterial, anticoagulation, endothelialization, drug delivery, and tissue regeneration.

Considering the great potential of functional polymers and the increasing requirement of biomedical applications, it is of high importance to better understand the biological behaviors at the interface between biological systems and polymeric materials. Moreover, the development of novel biomaterials with desired surface characters is required to meet the growing demand of the clinical applications.

Therefore, the editors are pleased to launch this special issue and invite researchers to contribute their reviews and original papers in the field of functional polymers for biointerface engineering.

Potential topics include but are not limited to the following:

• Polymeric biomaterials and the related interfacial properties
• Polymer coatings for biomedical applications
• Polymer coatings in tissue engineering applications
• Surface modification technologies of polymeric materials
• Interfacial interactions between biological systems and the polymeric materials
• Characterization of the surfaces and interfaces of functional polymers