Microscopic Polyangiitis in Systemic Sclerosis

Table 1

Comparison of clinical manifestations in MPA between French and Japanese studies.

	French study [4]	Japanese study [19]
Cases	85	63
Age, mean (range) years	56.8 (16–86)	59.0 (13–91)
Sex ratio, Male : Female	47 versus 38	19 versus 44
Fever	55.30%	71.00%
Weight loss	72.90%	42.90%
Skin involvement	62.40%	24.20%
Arthralgias	50.60%	62.90%
Myalgias	48.20%	50.80%
Renal involvement	78.80%	87.30%
Renal insufficiency	(47/67) 70.1%	49.20%
Rapidly progressive GN	—	66.70%
Proteinuria	(54/67) 80.6%	93.10%
Hematuria	(45/67) 67.2%	76.70%
Lung involvement	24.70%	63.50%
Alveolar hemorrhage	11.80%	22.20%
Pneumonitis	10.60%	33.30%
Pleiritis	5.90%	19.00%
Mononeuritis multiplex	57.60%	30.00%
Central nervous system involvement	11.80%	6.30%
Gastrointestinal tract involvement	30.60%	6.30%
Hypertension	34.10%	41.30%
Myocardial infarction	2.40%	1.60%
Pericariditis	10.60%	3.20%
Cardiac failure	17.60%	3.20%