Vasculitis in Systemic Sclerosis

Table 1

Seven cases of large-vessel vasculitis associated with SSc.

Case	Vasculitis	Age/Sex	Age at; SSc Dx	SSc; type	Age at Vasculitis Dx	Presentation	Diagnosis	Outcome
Perez-Jimenez; et al. [13]	GCA	68/F	68	L	70	Headache, jaw claudication; ESR 53	Temporal artery biopsy: inflammatory infiltrate, giant cells	Prednisone 60 mg daily x 5 weeks then tapered. Symptom-free at 5 years
Hupp [14]	GCA	70/F	?	L	70	Headache, jaw claudication; ESR 53	Temporal artery biopsy: mononuclear infiltrate, giant cells, destruction of internal elastic lamina	Prednisone 80 mg daily, tapered to 30 mg daily over 5 months. Symptom-free and ESR 3 at; 5 months.
Sari-Kouzel; et al. [15]	GCA	64/F	49	L	64	Gangrene of right 2nd and 3rd toes; ESR 14	Right knee amputation biopsy: mononuclear infiltrate, giant cells, vascular lumen occlusion	Prednisolone 30 mg daily, tapered to 10 mg daily over 6 months. Symptom-free at 6 months.
Passiu et al. [16]	TA	29/F	29	D	21	?	?	?
Yago et al. [17]	TA	68/F	66	D	66	Vertigo, bruits in neck, abdomen, and back; asymmetric blood pressure; in arms	Stenosis of right brachiocephalic trunk, celiac and left renal arteries	?
Kocabay et al. [18]	TA	48/F	48	D	47	Pulseless in both arms with intermittent claudication	Obliteration of bilateral subclavian arteries distal to vertebral artery bifurcation	?
Kim et al. [19]	TA	37/F	33	L	37	Weak left radial pulse	Stenosis of right common carotid artery, right external carotid artery, thoracic and abdominal aorta,; left brachial artery compression by scalenus muscle on abduction	?

GCA = giant cell arteritis; TA = Takayasu’s arteritis; SSc = systemic sclerosis; L = limited; D = diffuse; ESR = erythrocyte sedimentation rate.