Randomised Double-Blind Trial of Combination Antibiotic Therapy in Rheumatoid Arthritis

Table 3

Number and percentage of patients with an ACR20 response, together with the number of patients with a 20% improvement for each core variable. 20 after each variable indicates 20% improvement.

Variable	Placebo (𝑛=8)		Active (𝑛=12)		Placebo-active		𝑃 value
	Number	%	Number	%	Difference %	95% CI
ACR20	0	0	2	17	−17	−38 to 4	.5
Completed	8	100	7	58	42	14 to 70	.06
HAQ20	0	0	2	17	−17	−38 to 4	.5
VAS Assess.20	5	63	4	33	29	−14 to 72	.4
Pat. Pain20	1	13	3	25	−13	−46 to 21	.6
Pat. Dis. Assess.20	1	13	2	17	−4	−35 to 27	1.0
CRP20	3	38	4	33	4	−39 to 47	1.0
ESR20	5	63	1	8	54	17 to 91	.02
Swollen joint20	4	50	6	50	0	−45 to 45	1.0
Tender joint20	6	75	6	50	25	−16 to 66	.4