Low-Dose Naltrexone for Pruritus in Systemic Sclerosis
Figure 2
Biopsy specimens from patient 3: H&E-stained section shows scant perivascular inflammation and thickening of dermal collagen (20X). There are scattered mast cells in perivascular and interstitial distribution with granular-appearing cytoplasm (IHC mast cell tryptase 20X).