Effect of GS on IL-1β-induced gene expression of MMP-3 (a) and ADAM-TS5 (b). One hour after the pretreatment with GS (0,1–100 μM), SW1353 are stimulated with IL-1β (2 ng/mL) as indicated. Representative pictures of 3 to 5 independent experiments are shown. Data are mean ± SD of three replicates.