IgG4-Related Lymphadenopathy

Figure 6

Multicentric Castleman’s disease with abundant IgG4⁺ cells. (a) Atrophic germinal centers and interfollicular expansion are seen. (b) Sheets of proliferating mature plasma cells are present in the interfollicular zone. (c) The majority of mature plasma cells are positive for IgG4 (IgG4⁺/IgG⁺ plasma cell ratio >70%).

(a)

(b)

(c)