Controlled Cohort Study of Serum Gonadal and Adrenocortical Steroid Levels in Males Prior to Onset of Rheumatoid Arthritis (pre-RA): A Comparison to pre-RA Females and Sex Differences among the Study Groups
Table 3
Age-adjusted partial correlations of normalized imputed hormones (logs) in female pre-RA (top) and CN (bottom)*.
E2/test
OH-PREG
OH-P4
DHEA
ADIONE
Test
E2
Cortisol
DHEAS
LH
PRL
E2/test
0.213
0.473
0.11
−0.718
0.777
0.219
0.124
−0.332
−0.241
0.227
0.005
0.535
0.063
0.000
0.000
0.214
0.486
0.055
0.170
36
36
36
36
36
36
36
36
36
36
OH-PREG
−0.061
0.619
0.787
0.624
0.034
0.224
0.075
0.395
−0.071
0.012
0.473
0.000
0.000
0.000
0.846
0.196
0.667
0.019
0.686
0.943
144
36
36
36
36
36
36
36
36
36
OH-P4
0.229
0.704
0.342
0.439
−0.397
0.354
−0.239
0.220
−0.326
0.207
0.006
0.000
0.044
0.008
0.018
0.037
0.167
0.204
0.056
0.234
144
144
36
36
36
36
36
36
36
36
DHEA
−0.231
0.620
0.377
0.685
0.187
0.151
0.224
0.563
0.001
−0.151
0.006
0.000
0.000
0.000
0.281
0.385
0.195
0.000
0.994
0.388
144
144
144
36
36
36
36
36
36
36
ADIONE
−0.113
0.433
0.329
0.770
0.070
0.502
0.199
0.632
0.020
−0.069
0.181
0.000
0.000
0.000
0.689
0.002
0.251
0.000
0.908
0.693
144
144
144
144
36
36
36
36
36
36
Test
−0.778
0.231
−0.074
0.377
0.296
−0.191
0.057
−0.001
0.302
0.000
0.006
0.378
0.000
0.000
0.272
0.744
0.996
0.078
0.232
144
144
144
144
144
36
36
36
36
36
E2
0.548
0.169
0.350
0.088
0.173
0.017
0.115
0.094
−0.364
−0.105
0.000
0.044
0.000
0.296
0.039
0.839
0.518
0.591
0.032
0.547
144
144
144
144
144
144
35
36
36
36
Cortisol
−0.118
0.163
−0.103
0.173
0.040
−0.001
−0.196
−0.080
−0.092
−0.350
0.164
0.052
0.221
0.038
0.638
0.993
0.019
0.646
0.599
0.039
144
144
144
144
144
144
144
36
36
36
DHEAS
0.027
0.324
0.172
0.450
0.411
0.032
0.028
−0.059
0.186
−0.108
0.750
0.000
0.040
0.000
0.000
0.705
0.739
0.483
0.285
0.537
144
144
144
144
144
144
144
144
36
36
LH
−0.093
−0.045
−0.217
0.028
0.042
0.149
−0.016
0.105
−0.117
−0.103
0.273
0.594
0.009
0.736
0.618
0.077
0.851
0.214
0.165
0.555
144
144
144
144
144
144
144
144
144
36
PRL
0.094
−0.050
0.087
−0.142
−0.058
−0.199
0.031
0.037
−0.087
0.072
0.270
0.553
0.300
0.091
0.492
0.017
0.715
0.659
0.304
0.394
144
144
144
144
144
144
144
144
144
144
; (-to- method, validated as and , resp., in the MRA models, as specified in Section 2.3).