Possible Involvement of Foxp3+ Regulatory T Cells in the Development of Immune-Mediated Pancreatitis in MRL/Mp Mice Treated with Polyinosinic:Polycytidylic Acid
Figure 6
Representative H&E stained histological sections of the pancreases (a) and histopathological score of the pancreases (b) in poly I:C-treated MRL/Mp mice at the age of 10–20 weeks, along with Cerulein-, Ligation-, and -treated mice. In MRL/Mp, Ligation-, and -treated mice, representative pancreatic tissues showed diffuse parenchymal destruction, but with some parenchymal residue retained intact (grade 3). In Cerulein-treated mice, only slight edema was detected in the interstitium (grade 0). ×100 magnification (large panel), ×400(inset). Data are expressed as .
