Validation of a Prediction Rule for the Diagnosis of Rheumatoid Arthritis in Patients with Recent Onset Undifferentiated Arthritis

Table 5

Cost effectiveness ratio for complete van der Helm-van Mil prediction score, score without anti-CCP, score without RF, and score without anti-CCP and without RF.

Diagnostic score	Cost on 100 patients (US dollars)	Number of patients correctly diagnosed	Incremental cost	Incremental number of correctly diagnosed	ICER
vHvM without RF and without anti-CCP (cut off score >5.66)	1180	61	—	—	—
vHvM adding RF (without anti-CCP) (cut off score >6)	1380	64	200	4	50
vHvM adding anti-CCP (without RF) (cut off score >6.7)	7380	79	6200	18	344
complete vHvM (with anti-CCP and RF) (cut off score >6.94)	7580	80	6400	19	337

vHvM: van der Helm-van Mil prediction score; RF: rheumatoid factor; ICER: incremental cost effectiveness ratio.