Ectopic Germinal Centers and IgG4-Producing Plasmacytes Observed in Synovia of HLA-B27+ Ankylosing Spondylitis Patients with Advanced Hip Involvement

<div>Plasma cells in synovial tissue. (a) CD38 positive plasma cells near lymphocyte follicles in case 5 (DAB staining, 200x); (b) massive IgG-positive plasma cell presence in case 5 (AEC staining, 200x); (c) numerous IgG4-positive plasma cell in case 5 (AEC staining, 200x); and (d) IgG4-positive plasma cells in case 6 (AEC staining, 200x).</div>

International Journal of Rheumatology

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Figure 3

Figure 3: Ectopic Germinal Centers and IgG4-Producing Plasmacytes Observed in Synovia of HLA-B27+ Ankylosing Spondylitis Patients with Advanced Hip Involvement 

Figure 3 | Ectopic Germinal Centers and IgG4-Producing Plasmacytes Observed in Synovia of HLA-B27+ Ankylosing Spondylitis Patients with Advanced Hip Involvement 