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International Journal of Rheumatology
Volume 2015 (2015), Article ID 730285, 6 pages
http://dx.doi.org/10.1155/2015/730285
Research Article

Prevalence of Hyposalivation in Patients with Systemic Lupus Erythematosus in a Brazilian Subpopulation

1Department of Oral Pathology, University of Cuiabá, Avenida Manoel José de Arruda 3.100 Jardim Europa, 78065-900 Cuiabá, MT, Brazil
2Department of Pathology, Federal Fluminense University, Rua Marquês do Paraná 303, No. 4 Andar do Prédio Principal, Sala 1, 24.033-900 Niterói, RJ, Brazil
3Department of Pediatrics, School of Medicine, Federal University of Mato Grosso, Avenida Fernando Corrêa da Costa 2367, Boa Esperança, 78060-900 Cuiabá, MT, Brazil
4Department of Statistics, Institute of Exact Sciences, Federal University of Mato Grosso, Avenida Fernando Corrêa da Costa 2367, Boa Esperança, 78060-900 Cuiabá, MT, Brazil
5School of Dentistry, University of Cuiabá, Brazil Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil
6Department of Rheumatology, University of Cuiabá, Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil
7Faculty of Dentistry, University of Cuiabá, Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil

Received 30 September 2014; Accepted 16 December 2014

Academic Editor: Lisa Rider

Copyright © 2015 Cristhiane Almeida Leite et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Systemic lupus erythematosus (SLE) is a chronic inflammatory, multisystem, and autoimmune disease. Objective. The aim of this study was to describe the prevalence of hyposalivation in SLE patients and evaluate factors associated. Methods. This is a cross-sectional study developed at the Cuiaba University General Hospital (UNIC-HGU), Mato Grosso, Brazil. The study population consisted of female SLE patients treated at this hospital from 06/2010 to 12/2012. Unstimulated salivary flow rates (SFRs) were measured. Descriptive and inferential analyses were performed in all cases using a significance level . Results. The results showed that 79% of patients with systemic lupus erythematosus suffered from hyposalivation and that the disease activity and age in years were the factors that resulted in statistically significant differences. Conclusion. The activity of the disease, age >27 years, and the drugs used were factors associated with hyposalivation, resulting in a statistically significant decrease in saliva production.