Familial Mediterranean Fever in Iran: A Report from FMF Registration Center

Table 2

Results of MEFV genes mutations and different allele’s analysis.

Mutation	Genotype	Percent	Number
Heterozygote; (25.52%)	E148Q	8.7	21
	M694V	8.36	20
	V726A	2.5	6
	A744S	1.7	4
	M680I	2.1	5
	P396S	1.2	3
	R761H	0.84	2
Homozygote; (13.38%)	M694V-M694V	7.1	17
	M680I-M680I	2.92	7
	E148Q-E148Q	0.84	2
	M694I-M694I	0.84	2
	V726A-V726A	0.84	2
	P396S-P396S	0.42	1
	R761H-R761H	0.42	1
Compound heterozygote; (39.7%)	M694V-V726A	10.46	25
	E148Q-M694V	2.96	7
	M680I-V726A	6.27	15
	R761H-M694V	2.5	6
	M680I-M694V	2.5	6
	R761H-E148Q	0.42	1
	V726A-R761H	2.5	6
	M694V-M694I	0.84	2
	M680I-R761H	2.5	6
	M680I-E148Q	0.84	2
	E148Q-P396S	2.96	7
	A744S-R761H	0.42	1
	E148Q-V726A	1.69	4
	K694R-V726A	0.42	1
	E148Q-A744S	0.42	1
	E148Q-M694I	1.27	3
	M694I-M680I	0.42	1
	F497L-E148Q	0.42	1
Patient with no identified mutation; (21.33%)		21.33	50