Deferoxamine Suppresses Collagen Cleavage and Protease, Cytokine, and COL10A1 Expression and Upregulates AMPK and Krebs Cycle Genes in Human Osteoarthritic Cartilage

<div>Representative analyses of <sup>3</sup>[H]-thymidine incorporation (a) and <sup>3</sup>[H]-proline uptake (b) into OA articular cartilage explants in the absence and presence of 10–50 <i>μ</i>M DFO.</div>

International Journal of Rheumatology

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Figure 1

Figure 1: Deferoxamine Suppresses Collagen Cleavage and Protease, Cytokine, and COL10A1 Expression and Upregulates AMPK and Krebs Cycle Genes in Human Osteoarthritic Cartilage 

Figure 1 | Deferoxamine Suppresses Collagen Cleavage and Protease, Cytokine, and COL10A1 Expression and Upregulates AMPK and Krebs Cycle Genes in Human Osteoarthritic Cartilage 