The Diagnostic Value of Alpha-1-Antitrypsin Phenotype in Patients with Granulomatosis with Polyangiitis

Figure 1

Examples of A1AT phenotype patterns, obtained by IEF. Track 1: PiMS. Track 2: PiZZ. Track 3: PiMM. Track 4: PiMZ. Track 5: PiMF. Track 6: PiMM. А1АТ: alpha-1-antitrypsin. IEF: isoelectrofocusing. M2, M4, M6, M7, and M8: zones of migration of main A1AT isoforms in normal PiMM phenotype, detected by IEF. F, Z, and S: additional bands with another migration, indicating the presence of PiF, PiS, and PiZ alleles.